Our friends at the Dental Elf came across this systematic review of interventions for drooling in children with cerebral palsy, which we thought our readers may find useful.
Drooling can cause chapped or sore skin around the mouth and chin, and can lead to skin and mouth infections, dehydration, difficulties chewing and a range of other issues. The Cochrane review set out to evaluate the effectiveness and safety of interventions aimed at reducing or eliminating drooling in children with cerebral palsy.
The reviewers included only randomised controlled trials (RCTs) and controlled clinical trials (CCTs).
Six studies were included in the review. Four were trials using botulinum toxin-A (BoNT-A) and two were trials on the pharmacological interventions, benztropine and glycopyrrolate.
No RCTs or CCTs were retrieved on surgery, physical, oro-motor and oro-sensory therapies, behavioural interventions, intra-oral appliances or acupuncture.
A meta-analysis of the studies eligible for review was not possible, so a descriptive summary was provided.
All studies showed some statistically significant change for treatment groups up to 1 month post intervention. However, there were methodological flaws associated with all six studies.
The authors concluded
It was not possible to reach a conclusion on the effectiveness and safety of either BoNT-A or the pharmaceutical interventions, benztropine and glycopyrrolate. There is insufficient evidence to inform clinical practice on interventions for drooling in children with CP. Directions for future research are provided.Walshe M, Smith M, Pennington L. Interventions for drooling in children with cerebral palsy, Walshe M et al., Cochrane Database of Systematic Reviews 2012, Issue 2, http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008624.pub2/abstract
